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(3aR,4R,6S,6aS)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-(1-ethylpropyl)-3a,5,6,6a-tetrahydro-4H-cy

(1S-4R)-4-[[(1,1-diMethylethoxy)carbonyl]amino]- 2-Cyclopentene-1-carboxylic acid Methyl ester

CAS: 229613-93-8

Molecular Formula: C18H30N2O5

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(3aR,4R,6S,6aS)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-(1-ethylpropyl)-3a,5,6,6a-tetrahydro-4H-cy - Names and Identifiers

Name (1S-4R)-4-[[(1,1-diMethylethoxy)carbonyl]amino]- 2-Cyclopentene-1-carboxylic acid Methyl ester
Synonyms Peramivir Intermediate 2
Methyl (1S,4R)-4-[(tert-butoxycarbonyl)amino]cyclopent-2-ene-1-carboxylate
methyl 2-((1R,4R)-4-((tert-butoxycarbonyl)amino)cyclopent-2-en-1-yl)acetate
(1S-4R)-4-[[(1,1-diMethylethoxy)carbonyl]amino]- 2-Cyclopentene-1-carboxylic acid Methyl ester
(1S-4R)-4-[[(1,1-diMethylethoxy)carbonyl]aMino]- 2-Cyclopentene-1-carboxylic acid Methyl ester
2-cyclopentene-1-carboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, (1S,4R)-
(3aR,4R,6S,6aS)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-(1-ethylpropyl)-3a,5,6,6a-tetrahydro-4H-cy
Methyl 4-{[(tert-butoxy)carbonyl]aMino}-3-(pentan-3-yl)-3aH,4H,5H,6H,6aH-cyclopenta[d][1,2]oxazole-6-carboxylate
(3aR,4R,6S,6aS)-methyl4-(tert-butoxycarbonyl)-3-(pentan-3-yl)-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]isoxazole-6-carboxylate
(3Ar,4R,6S,6As)-Methyl 4-(Tert-Butoxycarbonyl)-3-(Pentan-3-Yl)-4,5,6,6A-Tetrahydro-3Ah-Cyclopenta[D]Isoxazole-6-Carboxylate
(3aR,4R,6S,6aS)-Methyl 4-(tert-butoxycarbonyl)-3-(pentan-3-yl)-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]isoxazole-6-carboxylate
(3aR,4R,6S)-Methyl-4-((tert-butoxycarbonyl)aMino)-3-(pentan-3-yl)-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]isoxazole-6-carboxylate
(3aR,4R,6S,6aS)-4-[[(1,1-DiMethylethoxy)carbonyl]aMino]-3-(1-ethylpropyl)-3a,5,6,6a-tetrahydro-4H-cyclopent[d]isoxazole-6-carboxylic Acid Methyl Ester
(3aR,4R,6S,6aS)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-(1-ethylpropyl)-3a,5,6,6a-tetrahydro-4H-cyclopent[d]isoxazole-6-carboxylic acid methyl ester
CAS 229613-93-8
EINECS 1308068-626-2
InChI InChI=1S/C12H19NO4/c1-12(2,3)17-11(15)13-9-6-5-8(7-9)10(14)16-4/h5-6,8-9H,7H2,1-4H3,(H,13,15)/t8-,9+/m1/s1

(3aR,4R,6S,6aS)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-(1-ethylpropyl)-3a,5,6,6a-tetrahydro-4H-cy - Physico-chemical Properties

Molecular FormulaC18H30N2O5
Molar Mass354.44
Density1.22±0.1 g/cm3(Predicted)
Melting Point67-69°C
Solubility Chloroform (Sparingly), Methanol (Slightly)
AppearanceSolid
ColorOff-White to Pale Beige
pKa11.61±0.60(Predicted)
Storage ConditionSealed in dry,Room Temperature

(3aR,4R,6S,6aS)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-(1-ethylpropyl)-3a,5,6,6a-tetrahydro-4H-cy - Introduction

(1S-4R)-4-[[(1,1-dimethylethoxy) carbonyl]amino]-Acetic Methyl ester ((1S-4R)-4-[[(1,1-dimethylethoxy) carbonyl]amino]-2-cyclopentene-1-carboxylic acid methyl ester) is an organic compound.

Nature:
-chemical formula: C17H27NO5
-Molecular weight: 325.4g/mol
-Appearance: White crystalline powder
-Melting point: 101-103 ° C
-Boiling point: 414.6 ° C
-Density: 1.129g/cm3

Use:
The compound is often used as a standard and reagent for high performance liquid chromatography (HPLC) chiral analysis. It is an important organic reagent for quantitative analysis and resolution of chiral solid phase organic reagents in chiral mixtures.

Method:
The compound can be amino-protected by (1S,4R)-4-hydroxy-2-cyclopentene-1-carboxylic acid methyl ester, it is then reacted with 1-ethylpropyl iodide in the presence of a base, followed by reduction and esterification with acetic acid.

Safety Information:
This compound is an organic compound and has a certain degree of danger. Pay attention to the following safety measures during operation and handling:
-Avoid contact with eyes, skin and clothing.
-Use protective gloves, goggles and laboratory ventilation during operation.
-If inhaled, move to a ventilated place and seek medical help.
-If it is splashed on the skin or eyes, rinse immediately with plenty of water and seek medical examination.
Last Update：2024-04-10 22:29:15
(3aR,4R,6S,6aS)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-(1-ethylpropyl)-3a,5,6,6a-tetrahydro-4H-cy
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CAS: 229613-93-8
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Email: 3008007409@qq.com
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QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
Hubei YoungXin Pharmaceutical Tech Co.,Ltd.
Spot supply
Product Name: Peramivir Impurity 5 Visit Supplier Webpage Request for quotation
CAS: 229613-93-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052 Click to send a QQ message
Wechat: 15671228036
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: (3aR,4R,6S,6aS)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-(1-ethylpropyl)-3a,5,6,6a-tetrahydro-4H-cy Visit Supplier Webpage Request for quotation
CAS: 229613-93-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
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(3aR,4R,6S,6aS)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-(1-ethylpropyl)-3a,5,6,6a-tetrahydro-4H-cy
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